The historical centre of Trepuzzi has  very beautiful case a corte and imposing noble residences like Spinelli Palace, built in the XVIII century the  Baronial Palace, that was erected in the XVII century on  a pre-existing fortress. It has been restored a lot of times and in the past the feudal vassals used to live here.  The main façade has a richly decorated portal on which you can see a civic coat of arms. Among the several religious monuments there is the Mother Church dedicated to Our Lady of the Assumption, built in 1603 (but it was first dedicated to St Peter). The imposing bell tower dates to the XVII century and it is very interesting. The main façade of the church has a beautiful front door and an ample window. The plant is  Latin cross and inside  you can admire some elegant baroque altars, a beautiful wooden pulpit, an XVIII century organ, some interesting canvasses representing holy scenes and a wooden choir. There is also a beautiful statue of the Holy Virgin Mary that, according to a popular story was the protagonist of a prodigious event. We are told that in 1779, when the French army arrived in the Salento the population of Trepuzzi was afraid. The people went to the Church to pray and ask the Madonna's help. Suddenly some drops of sweat appeared on the face of the Madonna and  the priest dried them  with a cloth. In the meantime  a dense fog covered Trepuzzi, thus saving this small town from the massacre of the enemies. In the public gardens you can also see a spire on which the visitors can admire the Madonna's statue, made at the beginning of the XIX century. The Neoclassic Church of  Our Lady of Sorrows was probably built in the XIX century and it is well decorated. The Church of St. Joseph was erected at the beginnings of the XVII century, on a pre-existing monument. The façade has a beautiful front door and some beautiful decorations. Near the Mother Church you can visit the simply decorated  Church of St Anthony Abbot, dating back to the XVII century. Also the Chapel of the Holy Cross was built in the XVII century and the façade is as simple as the inside. the Chapels of the Purification and of the Madonna of the Martyrs were built in the XVIII century. The protectress of Trepuzzi is Our Lady of the assumption, that is celebrated solemnly on August 15th.

The nickname of the inhabitants of Trepuzzi is "a 'nfacce a mmare" that means "in front of the sea" and it was invented by the malignant inhabitants of the near centres. In fact, according to a popular anecdote when the king went to Trepuzzi for a visit, he asked them which gift they wanted. They answered that they desired to move the village to the sea. The king, sarcastically, suggested them to tie a rope all around the village and to drag .